Financial, Ethical, Legal, And Social Considerations
Questions Bank
- DNA Structure and FunctionProtein SynthesisGenetic Influence on Cell Division, Differentiation, and GametogenesisPatterns of InheritanceEpigenetic Influences on Gene ExpressionAutosomal Inheritance and DisordersSex Chromosome and Mitochondrial Inheritance and DisordersFamily History and Pedigree ConstructionCongenital Anomalies, Basic Dysmorphology, and Genetic AssessmentEnzyme and Collagen DisordersCommon Childhood-Onset Genetic DisordersCommon Adult-Onset DisordersCardiovascular DisordersThe Genetics of CancerGenetic Contributions to Psychiatric and Behavioral DisordersGenetic and Genomic TestingAssessing Genomic Variation in Drug ResponseHealth Professionals and Genomic CareFinancial, Ethical, Legal, and Social ConsiderationsGenetic and Genomic Variation
Preimplantation genetic diagnosis provides parents with which options?
The ability to screen normally fertilized embryos for genetic traits after the first trimester
The ability to select embryos for implantation that test negative for a familial disease mutation
The opportunity to determine how many children they will conceive
The ability to guarantee that they will have a healthy baby
Your patient, Maggie, insists that her mother have genetic testing to determine if her breast cancer is connected to a mutation in the BRCA1/2 genes. Maggie isconcerned about her own risk for getting breast cancer and that of her children, but Maggie's mom does not want to be tested. What ethical principle is one of several that must be considered in evaluating this case?
Maggie's "autonomy"
Maggie's mother's "right to know"
The nurse's "duty to warn"
Maggie's mother's "right to privacy"
Apatient asks you whether the Genetic Information and Nondiscrimination Act (GINA) means that his insurance company is required to pay for his genetic testingif heelects to have it done. What is your best response?
"Yes, if you agree to share the test results with your family, your health-care provider, and your insurance company."
"Yes, if other family members have already been found positive for a disease-causing mutation."
"No, unless testing finds a specific disorder for which a current medical intervention has been proven effective."
"No, it only protects against discrimination and does not require insurance companies to pay for testing."
You are caring for a college professor who has been offered testing for her family's mutation in BRCA1. She expresses fear of genetic discrimination as a reason forrefusing genetic testing. What do you tell her?
"There is no need to be concerned about genetic discrimination."
"I appreciate your concern, but there is no way your insurance company or employer will ever be able to get your genetic testing results."
"There is now federal legislation banning genetic discrimination, and in addition, we will do everything we can to keep your results confidential."
"There have been no instances of documented genetic discrimination in insurance or employment. This concern is overblown."
Under which condition(s) would genetic testing for predisposition to an inherited disorder in a minor child be considered reasonable?
When the family pedigree indicates an autosomal-dominant pattern of inheritance
When the risk is high and prophylaxis to reduce the severity of the disorder is available
When penetrance is high and the expected onset is middle adulthood
When the mutation within a family is known and is specific