Regulation Of Gene Expression In Eukaryotes

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Question 1
Free
Short Answer

Please select the best match for each term.
A)Produces more than one protein from one gene
B)A method for targeting RNAs for degradation
C)Gene regulation dependant on parent of origin
D)A method of targeting proteins for degradation
E)Controls transcription initiation
-1)Alternative polyadenylation
2)Genomic imprinting
3)Enhancer
4)Ubiquitination
5)siRNA

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Question 2
Free
Multiple Choice

A similarity between regulation of the lac operon in bacteria and the regulation of galactose utilization in yeast is that both pathways

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A

transcribe all the genes necessary as one polycistronic mRNA.

B

use feedback inhibition to stop making their sugars.

C

use a modified version of their sugars as inducers.

D

are subject to catabolite repression.

E

C and D only

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Question 3
Free
Multiple Choice

When a promoter element is bound by a positive regulatory protein,the result is

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A

activation of replication.

B

activation of transcription.

C

activation of translation.

D

repression of replication.

E

repression of transcription.

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Question 4
Free
Multiple Choice

Unlike bacterial operons,eukaryotic operons

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A

are all positively controlled.

B

are all negatively controlled.

C

are restricted to certain eukaryotic kingdoms.

D

are exceedingly rare.

E

None of these

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Question 5
Free
Multiple Choice

Hormones can be considered

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A

inducers.

B

repressors.

C

transcription regulators.

D

translation regulators.

E

enzymes.

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Question 6
Multiple Choice

Unlike prokaryotes,most gene regulation in eukaryotes

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A
takes place at the transcriptional level.
B
is controlled at the level of transcript processing.
C
is controlled by inhibitory proteins.
D
is based on posttranslational modification.
E
None of these
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Question 7
Multiple Choice

Which of the following secondary structures may be a DNA-binding domain?

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A
Zinc finger
B
Leucine zipper
C
Helix-turn-helix
D
A and B only
E
A,B,and C
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Question 8
Multiple Choice

In eukaryotic cells,steroid hormones

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A
bind to cytoplasmic receptors,are transported to the nucleus,bind DNA,and regulate gene expression.
B
bind to cell surface receptors and send signals that result in regulation of genes in the nucleus.
C
act as enhancers and bind to an assortment of activators and repressors.
D
methylate DNA to regulate gene expression.
E
cause maternal effect.
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Question 9
Multiple Choice

RNA silencing involves

Choose correct answer/s
A
miRNAs.
B
siRNAs.
C
double-stranded RNA.
D
a protein called Dicer.
E
All of these
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Question 10
Multiple Choice

HREs are

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A
hormone receptors.
B
DNA sequences in promoter regions to which steroid hormone receptors bind.
C
proteins that interact with histones.
D
elements that lead to histone deacetylation.
E
None of these
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Question 11
Multiple Choice

Chromosome-level gene repression involves

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A
supercoiling.
B
physical blockage of gene regions.
C
chromatin formation.
D
nucleosomes.
E
All of these
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Question 12
Multiple Choice

Change in the DNA-histone complex that can increase or decrease transcriptional activity is termed

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A
induction.
B
gene regulation.
C
chromatin remodeling.
D
nucleosome formation.
E
None of these
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Question 13
Multiple Choice

The protein class(es)involved in the activation of transcription is (are)

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A
general transcription factors (GTFs).
B
transactivators.
C
coactivators.
D
A and B only
E
A,B,and C
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Question 14
Multiple Choice

Control of transcription initiation of eukaryotic protein-coding genes involves

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A
enhancers.
B
promoters.
C
repressors.
D
activators.
E
All of these
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Question 15
Multiple Choice

Activators in eukaryotes

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A
bind to enhancers.
B
may act as monomers
C
may act as homodimers.
D
may act as heterodimers with a DNA binding subunit and an activation subunit.
E
All of these
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Question 16
Multiple Choice

The half-life of a protein is directly related to

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A
what kind of cell it is produced in.
B
its tertiary structure.
C
whether it is encoded by a constitutively expressed gene.
D
its N-terminal amino acid residue.
E
the number of stabilizing cross-linkages.
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Question 17
Multiple Choice

Removal of the 5' G-cap of mRNA transcripts

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A
prevents transcript transport.
B
leads to degradation by exonucleases.
C
extends mRNA half-life.
D
leads to polyadelylation.
E
reduces mRNA half-life.
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Question 18
Multiple Choice

mRNA regulation can be achieved at the level of

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A
transport.
B
processing.
C
translation.
D
life span (degradation).
E
All of these
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Question 19
Multiple Choice

With respect to genetics,URS stands for

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A
uracil response system.
B
upstream regulatory sequence.
C
upstream repressor-binding sequence.
D
unregulated repression series.
E
uniform response system.
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Question 20
Multiple Choice

Proteins that are encoded by the same gene but differ in structure and function are the product of alternative splicing in pre-mRNA processing.Such protein variants are termed

Choose correct answer/s
A
isoteins.
B
heteromeric proteins.
C
isozymes.
D
protein isoforms.
E
allelomorphs.
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